Mechanical analysis in lamina cribrosa influence from angle-closure glaucoma

• Main Authors: Yue-Han Lyu, 呂岳翰
• Other Authors: 李宗翰
• Format: Others
• Language: zh-TW
• Published: 2014
• Online Access: http://ndltd.ncl.edu.tw/handle/f7yqup

碩士 === 淡江大學 === 機械與機電工程學系碩士班 === 102 === In this study, main research is focus on angle-closure glaucoma injure the laminacribrosa of eye ball. Due to the drainage system of aqueous humor blocked, cause the intraocular pressure of anterior chamber elevated. Intraocular pressure transfers load in glaucoma patients, leading to the optic nerve suffer oppression and yield visual field defect. So this study designed a complete eye model to analysis generating the pathogenesis of angle-closure glaucoma.We obtain the pressure values of the anterior chamber in this results, and it conform the range of clinical pressure values. From the phenomenon of stress distribution inside the eye, the maximum stress concentrate at posterior sclera and lamina cribrosa. Our study also conducted investigate for patients with different situations. Found that the eye organization are the same Young’s modulus, but the higher IOP make the phenomenon of stress concentration obviously in lamina cribrosa. And the same IOP, but the higher Young’s modulus of organization, it the best of ability to withstand the load.Lower Young’s modulus of eye organization, yielding the higher strain, and caused the great displacement in lamina cribrosa. This study analyzed the results of angle-closure glaucoma, make the patient to better understanding of their condition, and offer the important information to the next research.