| Summary: | 碩士 === 臺北醫學大學 === 保健營養學研究所 === 102 === According to 2005-2008 Nutrition and Health Survey in Taiwan （NAHSIT） the prevalence of metabolic syndrome is 57.3% in postmenopausal women. Metabolic syndrome is one of the risk factor of cardiovascular disease （CVD）. Postmenopausal women likely to have abdominal fat and visceral fat accumulation, abnormal lipid profile, increased CVD risk factors. Epidemiological studies suggest that consumption of tomato-based food might reduce the CVD risk. The aim of this study was to assess whether the consumption of tomato affects the risk factors of metabolic syndrome. We conduct a 8-week open-label, randomized controlled dietary intervention trial. Subjects were recruited from Taipei Medical University in October 2013, were randomly assigned into 2 groups, asked to consume a control （sprouts） diet and a tomato diet. Blood samples were collected at baseline and 8th week and were analyzed for lipid profile, blood sugar, antioxidant biomarkers-ferric reducing ability of plasma （FRAP） and serum carotenoids. Blood pressure, body weight, and body fat were also measured every week. After the 8 weeks dietary intervention, body weight, body mass index, waist circumference, hip circumference （p < 0.05） were significantly decreased in both group. Moreover, tomato group was significantly decreased on body weight and body fat mass, body fat percentage, waist circumference, hip circumference than control group. Tomato group was significantly decreased on serum total cholesterol, triglyceride, systolic blood pressure and blood sugar, and increased on high-density lipoprotein cholesterol, but not in control group. Antioxidant biomarkers-FRAP, beta-carotenoids and lycopene were significantly increased in tomato group, also not in control group. Therefore, tomato could reduce the risks of metabolic syndrome in postmenopausal women.
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