| Summary: | 碩士 === 大同大學 === 材料工程學系(所) === 102 === Titanium and its alloy are widely used as scaffolds, bone screw and bone plate. When metal implants in human body, immune system will attack the implant surface. Hence, resistance corrosion and biocompatibility have to be considered. In this study, the micro-arc oxidation used to formation a micro porous ceramic oxide layer film on Ti surface and also to improve the resistance corrosion. We introduced boundary layer by plasma enhanced chemical vapour deposition of hexamethyldisilazane (HMDSZ) organic silicide film and used Oxygen plasma to active this layer for provide free radicals to improve micro-arc oxidation surface’s bioinert. Then grafting polymerization of reactive monomer acrylic acid (AAc) by UV light graft therefore we can immobilize Chondroitin Sulphate, Chitosan or Gelatin on surface by crosslinking EDC/NHS.
As a result of, the increasing weight of substrates followed increasing micro-are oxidation treatment time. SEM micrographs showed that the coatings of surface becomes densifying after micro-are oxidized 15 min and it becomes smoother after 30min. From FTIR and ESCA, the C-6-S were successful immobilized on specimens. After MAO treated, the water contact angle of titanium sheets surface decrease less than 10° and wear resistance had been improved and all of best is 15min treatment time. Corrosion potential volts also enhanced from -0.4 V to -0.2~-0.3 V. After the plasma treatment, graft polymerization and immobilized different biomolecules on the surface had more effectively its characteristics.
With micro-arc oxidation time increases, rutile phase decreases and anatase phase increased. Finally in this study 3T3 Fibroblast cell was employed for cell attachment test, the plasma treatment and immobilized biomolecules chondroitin sulfate or gelatin are observed great attachment, the untreated Ti and UV-light grafted AAc were poor, relatively.
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