Identification of genes functioning as modifiers for the expression of expanded CUG RNA in C. elegans

碩士 === 國立中正大學 === 分子生物研究所 === 103 === Myotonic Dystrophy type 1 (DM1) is a dominant neuromuscular disease caused by CUG repeatexpansion. Mutant transcrip with expansion attracted RNA binding proteins, resulting in mis-regulation of alternative splicing and physiological toxicity. It has been shown...

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Bibliographic Details
Main Authors: Ya-Jeng Cheng, 鄭雅仍
Other Authors: Kuang-Ming Hsiao
Format: Others
Language:zh-TW
Published: 2015
Online Access:http://ndltd.ncl.edu.tw/handle/wcddzh