Safety and Detection Rate of Combined Ultrasound and Fluoroscopy-Guided Fiducial Marker Implantation for Liver CyberKnife Radiation Therapy

• Main Authors: Hua-Ming Cheng, 鄭華銘
• Other Authors: 鄭瑞棠
• Format: Others
• Language: zh-TW
• Published: 2015
• Online Access: http://ndltd.ncl.edu.tw/handle/d37n5d

碩士 === 長榮大學 === 醫學研究所 === 103 === Purpose: We want to know the possible complication rate and feasibility using guidance combined sonography and fluoroscopy to insert the fiducial marker into liver. Materials and Methods: In this study, the patients were retrospective reviewed from December 2008 to July 2014 at a medical center in the southern portion of Taiwan who receiving fiducial markers implantation for liver tumor before CyberKnife positioning. Totally there were 166 patients. We investigate the complication type and rate for patients receiving fiducial markers implantation. The correlation between the fluoroscopy detection rate during CyberKnife® radiotherapy and the possible patient or technical factors were analysed. Results: A total of 166 patients received implantation of fiducial marker in liver during this period of time. The complication rate was 2.5% and was associated with bleeding. Totally 129 patients completed the treatment of CyberKnife. There were 516 fiducial markers implanted (4 fiducials markers in every patient), of which 413 (80%) can be detected during the treatment. There were 111 patients (86%) that can be detected at least 3 fiducial markers. The migration rate was zero. There was no association about the detection of fiducial marker and location of tumor. Conclusion: Fiducial implantation under sonography guidance combined with fluoroscopy appears to be a safe and efficient procedure that the complications and migration rate is acceptable.