Short-term effects of coarse particulate air pollution on hospital admissions for cardiovascular diseases in Kaohsiung

• Main Authors: Ying-Cheng Cheng, 陳映辰
• Other Authors: Chun-Yuh Yang
• Format: Others
• Language: zh-TW
• Published: 2015
• Online Access: http://ndltd.ncl.edu.tw/handle/19461432392316044052

碩士 === 高雄醫學大學 === 職能治療學系碩士在職專班 === 103 === Abstract This study was undertaken to determine whether there was an association between coarse particles (PM2.5-10) levels and frequency of hospital admissions for cardiovascular diseases (CVD) in Kaohsiung, Taiwan. Hospital admissions for CVD including ischemic heart disease (IHD), stroke, congestive heart failure (CHF), and arrhythmias, and ambient air pollution data levels for Kaohsiung were obtained for the period from 2006-2010. The relative risk of hospital admissions for CVD was estimated using a case crossover approach, controlling for weather variables, day of the week, seasonality, and long term time trends. For the single pollutant model (without adjustment for other pollutants), increased rate of admissions for CVD were significantly associated with higher coarse PM levels only on cool days (< 250 C), with a 10 ug/m3 elevation in PM2.5-10 concentrations associated with a 3% (95% CI=2%-4%) rise in IHD admissions, 5% (95% CI=4%-6%) increase in stroke admissions, 3% (95% CI=1%-6%) elevation in CHF admissions, and 3% (95% CI=0%-6%) rise in arrhythmias admissions. No significant associations were found between coarse particle levels and number of hospital admissions for CVD on warm days. In the two-pollutant models, PM2.5-10 levels remained significantly correlated with higher rate of CVD admissions even controlling for sulfur dioxide, nitrogen dioxide, carbon monoxide, or ozone on cool days. Compared to effect estimate associated with a 10 ug/m3 increase in PM2.5 levels, effect estimates of frequency of CVD-related admissions associated with a 10 ug/m3 rise in coarse PM levels were weaker. This study provides evidence that higher levels of PM2.5-10 enhance the risk of hospital admissions for CVD.