Studies on Syntheses of Chiral 2,6-Disubstituted Piperidines and 5-Substituted Indolizidines: Applications on Total Syntheses of Dendrobatid Alkaloids (+)-167B and (+)-209D

碩士 === 國立中興大學 === 化學系所 === 103 === Indolizidine and quinolizidine alkaloids are medicinal compounds with potent biological activities. Here we present total syntheses of indolizidine (+)-167B and (+)-209D, featuring our developed preparation of enantiomerical tropanol derivatives, followed by functi...

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Main Authors: Hao-Yu Chen, 陳皓俞
Other Authors: Wen-Hua Chiou
Format: Others
Language:zh-TW
Published: 2015
Online Access:http://ndltd.ncl.edu.tw/handle/61634966772935321531
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spelling ndltd-TW-103NCHU50650812017-10-29T04:34:30Z http://ndltd.ncl.edu.tw/handle/61634966772935321531 Studies on Syntheses of Chiral 2,6-Disubstituted Piperidines and 5-Substituted Indolizidines: Applications on Total Syntheses of Dendrobatid Alkaloids (+)-167B and (+)-209D 手性2,6-二取代哌啶與5-取代吲哚里西汀之合成研究與箭毒蛙生物鹼(+)-167B與(+)-209D之全合成 Hao-Yu Chen 陳皓俞 碩士 國立中興大學 化學系所 103 Indolizidine and quinolizidine alkaloids are medicinal compounds with potent biological activities. Here we present total syntheses of indolizidine (+)-167B and (+)-209D, featuring our developed preparation of enantiomerical tropanol derivatives, followed by functional transformations to 2,6-disubstituted piperidine derivatives. Applications to Lasubines and Sparteine will be included. Wen-Hua Chiou 邱文華 2015 學位論文 ; thesis 73 zh-TW
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language zh-TW
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description 碩士 === 國立中興大學 === 化學系所 === 103 === Indolizidine and quinolizidine alkaloids are medicinal compounds with potent biological activities. Here we present total syntheses of indolizidine (+)-167B and (+)-209D, featuring our developed preparation of enantiomerical tropanol derivatives, followed by functional transformations to 2,6-disubstituted piperidine derivatives. Applications to Lasubines and Sparteine will be included.
author2 Wen-Hua Chiou
author_facet Wen-Hua Chiou
Hao-Yu Chen
陳皓俞
author Hao-Yu Chen
陳皓俞
spellingShingle Hao-Yu Chen
陳皓俞
Studies on Syntheses of Chiral 2,6-Disubstituted Piperidines and 5-Substituted Indolizidines: Applications on Total Syntheses of Dendrobatid Alkaloids (+)-167B and (+)-209D
author_sort Hao-Yu Chen
title Studies on Syntheses of Chiral 2,6-Disubstituted Piperidines and 5-Substituted Indolizidines: Applications on Total Syntheses of Dendrobatid Alkaloids (+)-167B and (+)-209D
title_short Studies on Syntheses of Chiral 2,6-Disubstituted Piperidines and 5-Substituted Indolizidines: Applications on Total Syntheses of Dendrobatid Alkaloids (+)-167B and (+)-209D
title_full Studies on Syntheses of Chiral 2,6-Disubstituted Piperidines and 5-Substituted Indolizidines: Applications on Total Syntheses of Dendrobatid Alkaloids (+)-167B and (+)-209D
title_fullStr Studies on Syntheses of Chiral 2,6-Disubstituted Piperidines and 5-Substituted Indolizidines: Applications on Total Syntheses of Dendrobatid Alkaloids (+)-167B and (+)-209D
title_full_unstemmed Studies on Syntheses of Chiral 2,6-Disubstituted Piperidines and 5-Substituted Indolizidines: Applications on Total Syntheses of Dendrobatid Alkaloids (+)-167B and (+)-209D
title_sort studies on syntheses of chiral 2,6-disubstituted piperidines and 5-substituted indolizidines: applications on total syntheses of dendrobatid alkaloids (+)-167b and (+)-209d
publishDate 2015
url http://ndltd.ncl.edu.tw/handle/61634966772935321531
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