A Study toward a Biomimetic Porous Titanium Scaffold by a Modified Hydrothermal Method

• Main Authors: Yu-HanSu, 蘇宇涵
• Other Authors: Jiunn-Der Liao
• Format: Others
• Language: zh-TW
• Published: 2015
• Online Access: http://ndltd.ncl.edu.tw/handle/56708773717998014244

碩士 === 國立成功大學 === 材料科學及工程學系 === 103 === Porous ceramic and polymer biomaterials are usually not suitable for load-bearing sites, but can be used for filling the cavities or regenerating the soft tissue. Porous titanium-based scaffolds are interesting, since they may have superior mechanical properties with high strength/weight ratios. Some alloying elements, e.g. ,Zr, Nb, Ta, Sn, Mo, Si, may lead to superior improvement in properties of titanium-based materials. Although its potential has been recognized for years, development of open porous structures has been hampered by limitations in production techniques. With the use of the techniques such as plasma spraying, space holder, common P/M, or sintered titanium-based fibers, it is still difficult to produce a porous structure with an expected architecture that meets both osteoconductive and mechanical requirements. To have the effect of osteoconduction, an “open interconnected” porous structure with pores in the range of 200-500 μm is estimated, though there is no exact agreement between scientists about the perfect size of pores to stimulate cells proliferation. From a mechanical point of view, the porous structure should be stiff enough to sustain physiological loads, but should not drastically exceed the stiffness of the bone being replaced to avoid stress shielding. As a consequence, to develop P/M sintered metal porous biomaterials for biomedical applications, it is required to compromise both properties and adjust their structural stability as a function of long-term employed time. In any case, the perspective is promising to focus upon metal porous biomaterials using P/M sintering technique, in particular for orthopedic and dental applications.