| Summary: | 碩士 === 國立中央大學 === 生物醫學工程研究所 === 103 === Sleep is an important procedure, which can reboot our brain and refresh our body. However, the sleep inertia occurred immediately after sleeping, if we did not have good sleep habit and efficient. Sleep inertia is transition state, which can attenuate our behavior/cognitive performance in a period of time. Until now, the mechanisms of sleep inertia are poorly understood, but suppose to the connections of brain networks did not recovered to the original level. Previous studies indicated that the sleep inertia duration may last minutes to hours, but rarely understand the brain working patterns during these times. In present study, we used the simultaneous EEG-fMRI recording to investigate the dynamic changes after awakening. We also combine the behavior and fMRI to observe the interactions between functional connectivity and βPVT. In the results, we found that the brain keeps the reorganization after awakening. The participant's behavior performance reaction time shows the significantly increased after awakening fifty minutes. ALFF did not show the difference in the lower frequency bands 0.01 to 0.1 Hz. Besides, we found the opposite phenomenon between behavior performance and βPVT. Furthermore, the different strength and specific changes occurred in the sensory motor network (SMN) after awakening, no matter in connectivity and PVT. It seems the brain have difference in dominant and non-dominant side during sleep inertia period. The thalamus connectivity and βPVT have significant decreased after awakening, but the connections between cortical/SMN was increased. We infer that thalamo-cortical play the key role to handle the sensory related functions during sleep inertia period, thereby affecting our behavior performance.
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