A novel Cullin4-based ubiquitin E3 ligase regulates PML proteasomal degradation to promote lung cancer progression

碩士 === 國立臺灣大學 === 生化科學研究所 === 103 === The PML (promyelocytic leukemia) protein plays pleiotropic roles in tumor suppression and its downregulation has been observed in multiple types of human cancers. While previous studies revealed the contribution of ubiquitin-proteasome system to PML degradation...

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Bibliographic Details
Main Authors: Jocelyn Fang-Yi Chen, 程方怡
Other Authors: Ruey-Hwa Chen
Format: Others
Language:zh-TW
Published: 2015
Online Access:http://ndltd.ncl.edu.tw/handle/83325079416148996869