Antifungal Activity of Cinnamic Acid Derivatives
碩士 === 國立臺灣大學 === 森林環境暨資源學研究所 === 103 === Cinnamon contains many aromatic compounds, among these compounds, trans-cinnamaldehyde has been proven to possess many bioactivities, and which belongs to trans-cinnamic acid derivatives in the biosynthesis pathway. The objective of this research is to find...
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ndltd-TW-103NTU053590212016-11-19T04:09:46Z http://ndltd.ncl.edu.tw/handle/83506275868488364942 Antifungal Activity of Cinnamic Acid Derivatives 肉桂酸類衍生物抑制真菌之活性 Shan-Yi Chou 周珊沂 碩士 國立臺灣大學 森林環境暨資源學研究所 103 Cinnamon contains many aromatic compounds, among these compounds, trans-cinnamaldehyde has been proven to possess many bioactivities, and which belongs to trans-cinnamic acid derivatives in the biosynthesis pathway. The objective of this research is to find more cinnamic acid dervitaves to against plant pathogenic fungi, wood rotting fungi and mildew, expecting to reduce the damage from fungi diseases. In order to evaluate antifungal activities of cinnamaldehyde congeners, we classified them into three groups, cinnamic acid congeners, cinnamaldehyde congeners and alkyl cinnamaldehyde congeners. Results demonstrated that trans-cinnamaldehyde had the best antifungal effects against Fusarium oxysporum, Trametes versicolor and Aspergillus terreus. Five compounds, p-methoxycinnamaldehyde, 2-methoxy cinnamaldehyde, α-methylcinnamaldehyde, α-amylcinnamaldehyde and α-hexyl cinnamaldehyde showed superior antifungal activities against Rhizoctonia solani, Colletotrichum gloeosporioides and Chaetomium globosm, which were better than that of trans-cinnamaldehyde. Besides, 2-methoxycinnamaldehyde, trans-cinnamaldehyde and p-methoxycinnamaldehyde were the top three compounds of inhibiting the mycelial growth of Ganoderma australe and Aspergillus niger. Furthermore, α-methylcinnamaldehyde showed the best antifungal ability against F. solani. With regard to wood rotting fungi, both 2-methoxycinnamaldehyde and trans-cinnamic acid could efficiently inhibited the mycelial growth of Lenzites betulina. And, 2-methoxycinnamaldehyde, p-methoxycinnamaldehyde and 4-hydroxy-3-methoxy cinnamaldehyde presented high antifungal activities against Laetiporus sulphureus. Finally, both α-amylcinnamaldehyde and 2-methoxycinnamaldehyde had better abilities to against Gloeophyllum trabeum than that of trans-cinnamaldehyde. 張惠婷 2015 學位論文 ; thesis 94 zh-TW |
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碩士 === 國立臺灣大學 === 森林環境暨資源學研究所 === 103 === Cinnamon contains many aromatic compounds, among these compounds, trans-cinnamaldehyde has been proven to possess many bioactivities, and which belongs to trans-cinnamic acid derivatives in the biosynthesis pathway. The objective of this research is to find more cinnamic acid dervitaves to against plant pathogenic fungi, wood rotting fungi and mildew, expecting to reduce the damage from fungi diseases.
In order to evaluate antifungal activities of cinnamaldehyde congeners, we classified them into three groups, cinnamic acid congeners, cinnamaldehyde congeners and alkyl cinnamaldehyde congeners. Results demonstrated that trans-cinnamaldehyde had the best antifungal effects against Fusarium oxysporum, Trametes versicolor and Aspergillus terreus. Five compounds, p-methoxycinnamaldehyde, 2-methoxy cinnamaldehyde, α-methylcinnamaldehyde, α-amylcinnamaldehyde and α-hexyl cinnamaldehyde showed superior antifungal activities against Rhizoctonia solani, Colletotrichum gloeosporioides and Chaetomium globosm, which were better than that of trans-cinnamaldehyde. Besides, 2-methoxycinnamaldehyde, trans-cinnamaldehyde and p-methoxycinnamaldehyde were the top three compounds of inhibiting the mycelial growth of Ganoderma australe and Aspergillus niger. Furthermore, α-methylcinnamaldehyde showed the best antifungal ability against F. solani.
With regard to wood rotting fungi, both 2-methoxycinnamaldehyde and trans-cinnamic acid could efficiently inhibited the mycelial growth of Lenzites betulina. And, 2-methoxycinnamaldehyde, p-methoxycinnamaldehyde and 4-hydroxy-3-methoxy cinnamaldehyde presented high antifungal activities against Laetiporus sulphureus. Finally, both α-amylcinnamaldehyde and 2-methoxycinnamaldehyde had better abilities to against Gloeophyllum trabeum than that of trans-cinnamaldehyde.
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author2 |
張惠婷 |
author_facet |
張惠婷 Shan-Yi Chou 周珊沂 |
author |
Shan-Yi Chou 周珊沂 |
spellingShingle |
Shan-Yi Chou 周珊沂 Antifungal Activity of Cinnamic Acid Derivatives |
author_sort |
Shan-Yi Chou |
title |
Antifungal Activity of Cinnamic Acid Derivatives |
title_short |
Antifungal Activity of Cinnamic Acid Derivatives |
title_full |
Antifungal Activity of Cinnamic Acid Derivatives |
title_fullStr |
Antifungal Activity of Cinnamic Acid Derivatives |
title_full_unstemmed |
Antifungal Activity of Cinnamic Acid Derivatives |
title_sort |
antifungal activity of cinnamic acid derivatives |
publishDate |
2015 |
url |
http://ndltd.ncl.edu.tw/handle/83506275868488364942 |
work_keys_str_mv |
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