Response of Multi Physiological Parameters Evoked by Heat Pain

• Main Authors: Jing-Siang Lin, 林敬祥
• Other Authors: Chiung-Cheng Chuang
• Format: Others
• Language: zh-TW
• Published: 2016
• Online Access: http://ndltd.ncl.edu.tw/handle/35711796034232347545

碩士 === 中原大學 === 生物醫學工程研究所 === 104 === Pain is a feeling that everyone experiences, and it can be an unpleasant and negative emotional experience. People sometimes seek medical treatment for the most common causes of pain. In clinical practice, a breakdown of doctor-patient communication and medical staff shortages can lead to unrelieved pain experienced by patients. In 2001, the Joint Commission Accreditation of Health Care Organization (JCAHO), which regards pain as fifth vital sign, and the inclusion of hospital accreditation item, has stressed the need for pain levels to be monitored at all times with any changes recorded. However, establishing effective continuous pain monitoring and management remains a challenge. In our research, we produced an induced heat pain stimulation and observed a variety of physiological parameters associated with the sympathetic nervous system such as Electrocardiography, Photoplethysmography and Galvanic skin response, with continuous observation of the changes in these physiological parameters when pain occurs. Through continuous monitoring, we aimed to determine a highly sensitive parameter that correlates with pain occurrence in order to improve the quality of clinical pain management. In this study, we included 35 effective samples in total, with 25 from the experimental group and 10 from the control group. After heat pain stimulation, statistical analysis showed that there were significant differences between the groups in the Numeric Rating Scale. Then, we found that heart rate variability and PPG were significantly different after heat pain stimulation. We hypothesize that the heat pain stimulus caused sympathetic nerve excitation and suppressed parasympathetic nerve activation while increasing the heart rate and high and low frequency changes occurred when the pain intensified. Additionally, when the arterial pressure dropped too low in vivo, the baroreceptor reflex regulated the equilibrium and promoted a return to normal blood pressure. According to the resultant phenomena of the experiment, multi physiological parameters would changed during heat stimulation. Clinicians may use this non-invasive technical to further monitor and evaluate the pain.