| Summary: | 碩士 === 國立臺灣大學 === 資訊管理組 === 104 === The cost of antibiotics remains high for hospitals, and inappropriate antibiotic use may lead to increased resistance to antibiotics.
In current stuies, patients admitted in the first quarter (January to March) of the year before and after implementation of the program were in cluded. The impacts of intensive antibiotic stewardship programs were analyzed by comparing indicators including related antibiotic costs, antibiotic consumptions and bacterial susceptibilities.
Among the total of 22,145 hospitalized-days, the sample sizes for two periods (before and after the implemented programs) were similar (11,387 vs 10,758).
The expenses incurred for antibiotics administered to hospital inpatients reduced from NT$517,974 (27.73% of the expenses on drugs administered to hospital inpatients) to NT$330,172 (19.01% of the expenses on drugs administered to hospital inpatients). Antibiotic consumption was also evaluated by collecting drug-users records obtained from the pharmacy according to the concept of the defined daily doses (DDDs). Consumption of antibiotics decreased by 40.97% (5532 vs 9371) compared to te basal study period.
The overall incidence of healthcare-associated infection did not decline significantly. The susceptibilities of the bacterial organisms isolated from the patients of the healthcare-associated infections towards antibiotics did not decline significantly.
Our experience could be a reference for developing individual antibiotic stewardship at peer hospital. We wish to reduce medical expenditure and improve patient safety by continued attainment of computer-assisted antimicrobial stewardship.
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