A Pipeline to Detect Genetic Modifiers by Using Targeted Sequencing
碩士 === 國立陽明大學 === 生物醫學資訊研究所 === 104 === Many neurodegenerative diseases are caused by expanded CAG repeat sequence, which encoding a polyQ tract in disease proteins. These abnormal proteins are highly susceptible to misfolding and aggregation, which lead to cytotoxicity and neuronal cell death. Prev...
Main Authors: | Kai-Lun Chin, 金凱倫 |
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Other Authors: | Ueng-Cheng Yang |
Format: | Others |
Language: | zh-TW |
Published: |
2016
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Online Access: | http://ndltd.ncl.edu.tw/handle/cgm2a5 |
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