Studies on the Development of Medicines for Fighting Neurodegenerative Diseases: Synthesis of sphingosine and Ganglioside Neu5GcHp-s1 and it’s Analogues with Various Ceramides

碩士 === 中原大學 === 化學研究所 === 105 === This paper aims to complete neurodegenerative activity of ganglioside Hp-s1 analogues Hp-SJ1、Hp-SJ2、Hp-SJ3 synthesis, we used chemoselective glycosylation reaction and [1+1+2] synthetic strategy. In addition, the synthesis of the sphingosine derivative xyl-13 will b...

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Main Authors:	Jain-Ming Chen, 陳建銘
Other Authors:	Yow-Fu Tsai
Format:	Others
Language:	zh-TW
Published:	2017
Online Access:	http://ndltd.ncl.edu.tw/handle/64994835480195387779

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spelling	ndltd-TW-105CYCU50650402017-09-22T04:33:53Z http://ndltd.ncl.edu.tw/handle/64994835480195387779 Studies on the Development of Medicines for Fighting Neurodegenerative Diseases: Synthesis of sphingosine and Ganglioside Neu5GcHp-s1 and it’s Analogues with Various Ceramides 治療神經退化疾病之藥物的開發研究：神經鞘胺醇的製備與唾液酸醣苷神經鞘醯胺Neu5GcHp-s1及其具多樣性神經鞘醯胺之類似物合成 Jain-Ming Chen 陳建銘碩士中原大學化學研究所 105 This paper aims to complete neurodegenerative activity of ganglioside Hp-s1 analogues Hp-SJ1、Hp-SJ2、Hp-SJ3 synthesis, we used chemoselective glycosylation reaction and [1+1+2] synthetic strategy. In addition, the synthesis of the sphingosine derivative xyl-13 will be carried out to synthesize the ceramide. The synthesis of Hp-SJG1, Hp-SJG2 and Hp-SJG3 main architectures NGLA-1, NGLR-1 and NGLM-1 has been completed. Yow-Fu Tsai 蔡祐輔 2017 學位論文 ; thesis 187 zh-TW
collection	NDLTD
language	zh-TW
format	Others
sources	NDLTD
description	碩士 === 中原大學 === 化學研究所 === 105 === This paper aims to complete neurodegenerative activity of ganglioside Hp-s1 analogues Hp-SJ1、Hp-SJ2、Hp-SJ3 synthesis, we used chemoselective glycosylation reaction and [1+1+2] synthetic strategy. In addition, the synthesis of the sphingosine derivative xyl-13 will be carried out to synthesize the ceramide. The synthesis of Hp-SJG1, Hp-SJG2 and Hp-SJG3 main architectures NGLA-1, NGLR-1 and NGLM-1 has been completed.
author2	Yow-Fu Tsai
author_facet	Yow-Fu Tsai Jain-Ming Chen 陳建銘
author	Jain-Ming Chen 陳建銘
spellingShingle	Jain-Ming Chen 陳建銘 Studies on the Development of Medicines for Fighting Neurodegenerative Diseases: Synthesis of sphingosine and Ganglioside Neu5GcHp-s1 and it’s Analogues with Various Ceramides
author_sort	Jain-Ming Chen
title	Studies on the Development of Medicines for Fighting Neurodegenerative Diseases: Synthesis of sphingosine and Ganglioside Neu5GcHp-s1 and it’s Analogues with Various Ceramides
title_short	Studies on the Development of Medicines for Fighting Neurodegenerative Diseases: Synthesis of sphingosine and Ganglioside Neu5GcHp-s1 and it’s Analogues with Various Ceramides
title_full	Studies on the Development of Medicines for Fighting Neurodegenerative Diseases: Synthesis of sphingosine and Ganglioside Neu5GcHp-s1 and it’s Analogues with Various Ceramides
title_fullStr	Studies on the Development of Medicines for Fighting Neurodegenerative Diseases: Synthesis of sphingosine and Ganglioside Neu5GcHp-s1 and it’s Analogues with Various Ceramides
title_full_unstemmed	Studies on the Development of Medicines for Fighting Neurodegenerative Diseases: Synthesis of sphingosine and Ganglioside Neu5GcHp-s1 and it’s Analogues with Various Ceramides
title_sort	studies on the development of medicines for fighting neurodegenerative diseases: synthesis of sphingosine and ganglioside neu5gchp-s1 and it’s analogues with various ceramides
publishDate	2017
url	http://ndltd.ncl.edu.tw/handle/64994835480195387779
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Studies on the Development of Medicines for Fighting Neurodegenerative Diseases: Synthesis of sphingosine and Ganglioside Neu5GcHp-s1 and it’s Analogues with Various Ceramides

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