The Protease Inhibition and Antioxidant Activities of Synthesized Peptides Based on the Rice Coleoptile Trypsin Inhibitor
碩士 === 國立成功大學 === 化學系 === 105 === Three peptides based on the rice coleoptile trypsin inhibitor were designed and synthesized. These synthesized peptides were further to assay their activity toward inhibiting the trypsin and α-chymotrypsin activity by using L-BAPNA and BTEE as substrate, respectivel...
| Main Authors: | , |
|---|---|
| Other Authors: | |
| Format: | Others |
| Language: | zh-TW |
| Published: |
2018
|
| Online Access: | http://ndltd.ncl.edu.tw/handle/f6vxw5 |
| Summary: | 碩士 === 國立成功大學 === 化學系 === 105 === Three peptides based on the rice coleoptile trypsin inhibitor were designed and synthesized. These synthesized peptides were further to assay their activity toward inhibiting the trypsin and α-chymotrypsin activity by using L-BAPNA and BTEE as substrate, respectively.
The result showed that three peptides do have the obviously activity to inhibit the trypsin showing non-competitive, partial uncompetitive and uncompetitive inhibition mode but they didn’t show the activity to inhibit the α-chymotrypsin. The antioxidant assays were carried out using DPPH as the substrate and showed these peptides all have antioxidant potential.
|
|---|