| Summary: | 碩士 === 國立中央大學 === 光電科學與工程學系 === 105 === Surface plasmon resonance (SPR) is the collective electron oscillation at the interface of metal and dielectric material. The SPR effect is highly sensitive to the change of surface refractive index, and therefore can be used to detect biomolecular binding events between the antibody and the antigen.
In this research, we present theoretical analyses on the potential of nitride-based SPR structure in biosensing applications. The SPR effect is achieved with a GaN/InGaN/GaN quantum well and a thin Ag layer, and the change in surface refractive index is detected by the varied emission intensity from the quantum well. The nitride epilayers were grown with metal-organic chemical vapor deposition (MOCVD). The MOCVD technique can easily produce wafer-scale nanostructures that are suitable for single-molecule detection with the surface enhanced Raman scattering (SERS) effect. With the calculated dispersion curves and the penetration depths estimated by the finite-difference time-domain method, we demonstrate the advantages of this novel SPR biosensing structure, which are not attainable with the conventional Kretschmann configuration.
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