| Summary: | 碩士 === 國立嘉義大學 === 生化科技學系研究所 === 105 === Diabetes is one of the largest global health issues in the world. The International Diabetes Federation estimate there are now 415 million adults aged 20-79 with diabetes worldwide. The prevalence of diabetes and related healthcare expenditures are higher global burden in Taiwan. Exercise along with dietary and pharmacological controls is suggested for managing diabetes. Okra has been one of newly cultivated vegetables in recent years. The functional ingredients of Okra include polysaccharides and flavonoids. Recent studies have demonstrated that okra may provide antioxidative, antibacterial, hepatorprotecetive, hypolipidemic and hypocholesterolemic effects. In this study, the okra extract was isolated by the ultrasonic extraction technology. In addition to control group, rats fed with high-fat diet (HFD) were induced to develop type 2 diabetes by intraperitoneal injection of STZ-nicotinamide. After four weeks, the results showed that ultrasonic extracts from okra significantly decreased postprandial blood glucose. In addition, diabetic rats treated with okra extracts displayed significantly decreased triacylglycerol, total cholesterol content in serum. In conclusion, the ultrasonic extraction of okra significantly improve postprandial blood glucose and hypolipidemia in type 2 diabetic rats.
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