| Summary: | 碩士 === 國立臺灣大學 === 電機工程學研究所 === 105 === Automated whole breast ultrasound (ABUS) has been widely used as a screening modality for examination of breast abnormalities. Reviewing hundreds of slices produced by ABUS, however, is time-consuming. Therefore, in this study, a fast and effective computer-aided detection (CADe) system based on 3-D convolutional neural networks (CNN) and prioritized candidate aggregation is proposed to accelerate this reviewing. Firstly, an efficient sliding window method is used to extract volumes of interest (VOIs). Then, each VOI is estimated the tumor likelihood with a 3-D CNN, and VOIs with higher estimated likelihood are selected as tumor candidates. Since the candidates may overlap each other, a novel scheme is designed to aggregate the overlapped candidates. During the aggregation, candidates are prioritized based on estimated tumor likelihood to alleviate over-aggregation issue. The relationship between the sizes of VOI and target tumor is optimally exploited to effectively perform each stage of our detection algorithm. On evaluation with a testing set of 192 tumors, our method achieved sensitivities of 95% (184/194), 90% (175/194), 85% (165/194), and 80% (155/194) with 2.9, 2.0, 1.3, and 0.8 FPs per pass, respectively. In summary, our method is more general and much faster than preliminary works, and demonstrates promising results.
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