| Summary: | 碩士 === 輔仁大學 === 營養科學系碩士班 === 106 === The Nutrition and Health Survey in Taiwan 2013-2015 showed the prevalence of osteoporosis over 50 years old is 12.3%. The greatest concern with osteoporosis is bone fracture which results in serious impact on one’s health and quality of life. The relationship among selenium (Se) and aluminum (Al) intake, blood Se and Al levels and bone mineral density (BMD) has not been studied. There are no dietary Al nad Se intake has not been studied in Taiwan. The purpose of this research is developing and validating a food frequency questionnaire (FFQ) to assess calcium (Ca), magnesium (Mg), Se and Al intakes. Sixty eight fractures subjects and forty nine age- and gender-matched non-fracture subjects were recruited. The trained interviewer conducted the ‘Bone Health and Calcium, Magnesium, Selenium, and Aluminum Food Frequency Questionairre’and arranged blood tests and BMD measurements for subjects. In addition, non-fracture subjects were interviewed and provided one-day 24 hours dietary recall (24HR) as a reference method of food frequency questionnaire. Among all subjects, average intake of Ca, Mg, Se and Al from FFQ are 680 ± 470 mg/d, 363 ± 228 mg/d, 143.0 ± 66.8 μg/d, and 0.6 ± 0.4 mg/d respectively. Ca (r=0.373; p=0.008), Mg (r=0.552; p=0.000) and Se (r=0.321; p=0.024) intakes assessed by FFQ and 24HR in non-fracture subjects were related. Mg intake from FFQ in non-fracture subjects was higher than fracture subjects (p=0.016). A significant linear relationship was found between Se intakes from FFQ and plasma Se (r=0.187 p=0.046). Mg intake was correlated to BMD of total hip (r=0.245; p=008), femoral neck (r=0. 229; p=0. 013), and trochanter (r=0.234; p=0.011). Se intake was correlated to BMD of total hip (r=0.243; p= 0. 008), femoral neck (r=0.192; p=0.039), and trochanter (r=0.230; p=0.013). A significant odds ratio was found between Mg intakes and risk of fracture (OR=0.343, 95% CI: 0.136–0.870). Plasma Se was correlated with all site of BMD (p<0.05). The FFQ of this research could be applied to assess Ca, Mg, and Se intake.
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