The Development of Multi-Material 3D Bioprinter via Changeable Printheads

• Main Authors: Shang-Yi Yang, 楊上逸
• Other Authors: Yih-Lin Cheng
• Format: Others
• Language: zh-TW
• Published: 2018
• Online Access: http://ndltd.ncl.edu.tw/handle/3nhk62

碩士 === 國立臺灣科技大學 === 機械工程系 === 106 === 3D Bioprinting Technique has been widely commercialized by many companies in recent years. The present 3D bioprinter is based on Extrusion-based Bioprinting Technique for most, which are mostly fixed printhead types that must be replaced and corrected before printing if needed. However, most of the bioprinters are unable to perform printing and replacement of the printheads/materials during printing, thus limiting the possibility of printing material combinations. Therefore, this study intends to develop multi-material pr inthead module with selectively and ease of operation, and then develop a 3D composite bioprinting system. At present stage, the bioprinter designed in this study has the ability to bioprint up to four different biomaterials in a single printing process, while the air pressure is used as the working fluid of the bioprinter. One of the printhead has a light source curing module to cure the biomaterial containing the photoinitiator. This study integrate the FDM slicing software with the CNC controller, so that the users can design pattern and facilitate printing according to their needs. The most distinctive feature of bioprinter in this study is that the four sets of printhead modules can expand the type of printhead according to the needs of future. Also, the printing materials and printheads can be selected and matched according to different needs. In addition, the bioprinter of this study will introduce common biological materials for printhead module printing test, in order to verify that the design of the mechanism can smoothly stack the materials.