Synthesis of 1,8 - Naphthalimide derivatives for potential anticancer drugs

碩士 === 淡江大學 === 化學學系碩士班 === 106 === The 1,8 - Naphthalimide derivatives are widely used in the synthesis of anticancer drugs. The activity of these compounds embed in DNA has been tested and the results are very good. In recent years, many scientists have devoted themselves to the study of new synth...

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Bibliographic Details
Main Authors: Wei – Ting Kao, 高維廷
Other Authors: Tzenge-Lien Shih
Format: Others
Language:zh-TW
Published: 2018
Online Access:http://ndltd.ncl.edu.tw/handle/ayfx9g
Description
Summary:碩士 === 淡江大學 === 化學學系碩士班 === 106 === The 1,8 - Naphthalimide derivatives are widely used in the synthesis of anticancer drugs. The activity of these compounds embed in DNA has been tested and the results are very good. In recent years, many scientists have devoted themselves to the study of new synthetic methods of synthesizing of 1,8 - Naphthalimide derivatives. It has been found that these compounds embedded in breast cancer cells, colorectal cancer cells, and lung cancer cells very well. We designed two series of derivatives and hope to further study their applications in the future.