| Summary: | 碩士 === 輔英科技大學 === 護理系碩士班 === 107 === Purpose: Schizophrenia is a condition that causes disability and serious mental illness. It not only affects the patient itself, but also affects the physical and mental health of the caregiver, and even has a profound impact on society. Patients with psychosis who are stable at home-care have different long-acting injection antipsychotics compared with oral psychiatric drugs, and whether the patients' attitude toward medication、side effects,、quality of life and quality of life of the caregivers are different.
Methods: This study adopted a longitudinal study design, collected from patients with schizophrenia who had been home-care for more than 6 months, and applied 45 patients with antipsychotic long-acting injections and oral medications and their caregivers. Data were collected at the beginning of the trial and three months after the receipt of the case to explore the differences in the continued effectiveness of the patient and the primary caregiver in the outcome variables.
Results: Home-care patients with schizophrenia, the long-acting injection antipsychotics group had no significant difference in drug attitudes and drug side effects between the two groups compared with the oral drug group. The patient's quality of life "autonomy" was significantly higher in patients with a lower pre-measured value (<9.95) and in patients with a larger "social function" (>7.83). The long-acting injection antipsychotics group was significantly higher than the oral drug group. The quality of life of the caregivers of the long-acting injection group of the oral drug group was significantly higher in the "social category".
Conclusion: When the patients are relatively stable, the effect of long-acting injection antipsychotics compared with oral medications can improve the quality of life of patients, but it does not significantly improve the quality of life of the caregivers. It can be seen that the quality of life of caregivers is not solely due to drug attitudes and drugs. There are still other factors worth exploring in terms of side effects and the quality of life of patients.
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