Structure of Zinc Ion Hydrogel Sensor Tip

• Main Authors: Fang, Teng-Chin, 方騰慶
• Other Authors: 孟心飛
• Format: Others
• Language: zh-TW
• Published: 2019
• Online Access: http://ndltd.ncl.edu.tw/handle/xbwxms

碩士 === 國立交通大學 === 物理研究所 === 107 === The thesis is mainly about minimize the sensor by the improved Zinc ion tip structure. The sensor tip is made cylindrically by the methods of stereo lithography, and it is cylindrical symmetric single optical fiber sensor. Sensing layers are made by the zinc ion sensing molecule TPN-Cl2which is provided by prof. Chen-Hsiung Hung of Institute of Chemistry, Academia Sinica. Mixed it with fixed ratio hydrogel Poly-HEMA molecules. Then put the layers on to the improved zinc ion structure, the single optical fiber sensor was made. The process of this study is helpful to the minimizing the sensor, also has a great affect in the used of biomedical measurement. The thesis can be simply separate into two parts of discussion: First part will be the background and the motivation of this study, also the theory of the detection of the Zinc ion and material that we used. At last, we will move on to the measure and process equipment. Second part, we will elaborate the consequence at the early stage, such as the process and the measurement part. From the result we can knew the importance of the wave guide layer, and the limit of size of the hydrogel layer sensor, with these points we can develop new tip structure. Tried HEMA monomer and UV resin as the material of the tip structure. We put external light outside the sensor on the analyte And test out it’s sense limit to confirm that the sensor’s effective discrimination in low concentration and do the measurement repeatedly, meanwhile because the external short wavelength light outside the sensor will cause some influence on the cell when cell measurement goes on, so we also done observation of sensor behavior under the long wavelength light for zinc sample. Hope it can increase the possibility that be used in the co-measurement with Taipei General Veteran Hospital. To summarize, for the future development, we could try illuminate inside and accept the signals, the result will approach the ideal case of needle tip sensor. It’s a big contribution for clinical research of biomedical.