| Summary: | 博士 === 國立臺灣大學 === 光電工程學研究所 === 107 === Optical Coherence Tomography (OCT) system is one of a potential image diagnostic technique to explore the diversity in bio-cell for subwavelength structures (microstructure) or quickly diagnosing the diseases for improving the cure rate in biomedical fields. In general OCT, the OCT signals against depth can mainly provide by measuring interference patterns from reference arm and the backscattering light of samples at optical system, and the high axial resolution can be provided with low coherence light source. The features of OCT can approach the cross-section images techniques (2D) or 3D-image by combining A-scans (axial, mode) and B-scans （lateral, mode）to clearly obtain the axial microstructures for biological tissues. In the field for extracting the optical information of measured sample within the OCT signal have been a popular issue recently. In this work, we are going to study this issue and corresponding applications by mainly utilized the mesoporous TiO2 beads films with diameter size for 20, 150, 300, and 500 nm as our non-biological sample and discuss the optical scattering properties of single- and multiple- scattering effects. With the extended Huygens Fresnel theory, the contribution of single- and multiple- scattering composition can be provided. Further, for precisely distinguishing and quantifying the optical properties of scattering coefficient in measured samples, we provide a new analysis flow combining the FDTD simulation method with OCT. The light scattering interactions in near- and far-field patterns between adjacent TiO2 beads can be determined and show in FDTD simulation method to identify the two optical parameters of anisotropy g factor and scattering coefficient in EHF model.
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