Development and characterization of methotrexate loaded poly(L-lactic acid) microspheres for the treatment of rheumatoid arthritis

Methotrexate (MTX) has shown anti-inflammatory effects in the treatment of rheumatoid arthritis. Attempts by other groups have been made to improve the efficacy and reduce toxicity by administering the drug intra-articularly, but the outcomes were not successful due to rapid clearance of the drug...

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Bibliographic Details
Main Author: Liang, Sanching Linda
Language:English
Published: 2010
Online Access:http://hdl.handle.net/2429/18404