Development and characterization of methotrexate loaded poly(L-lactic acid) microspheres for the treatment of rheumatoid arthritis
Methotrexate (MTX) has shown anti-inflammatory effects in the treatment of rheumatoid arthritis. Attempts by other groups have been made to improve the efficacy and reduce toxicity by administering the drug intra-articularly, but the outcomes were not successful due to rapid clearance of the drug...
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Language: | English |
Published: |
2010
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Online Access: | http://hdl.handle.net/2429/18404 |