Regulatory mechanisms of the exchange factor RasGRP1
RasGRP1 is an intracellular signaling protein expressed in lymphocytes that is responsible for activating Ras GTPases. Positive regulation of RasGRP 1 requires translocation to cellular membranes where lipid-anchored Ras can be accessed. Plasma membrane localization of RasGRP 1 in response to antige...
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| Format: | Others |
| Language: | English |
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University of British Columbia
2008
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| Online Access: | http://hdl.handle.net/2429/2861 |