Mode of action of mutagenic and oncogenic synthetic quinoline N-oxides

The molecular events in cells exposed to mutagenic and oncogenic quinoline N-oxides were examined by analyzing single-strand breakage of DNA. Secondary cultures of embryonic Syrian-hamster cells and a line of BHK-21 cells were used. The choice of nitroquinoIine N-oxides afforded a series of water-s...

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Bibliographic Details
Main Author: Laishes, Brian Anthony
Language:English
Published: University of British Columbia 2011
Subjects:
DNA
Online Access:http://hdl.handle.net/2429/34142