The contribution of different domains of connexin 43 to cytoskeletal rearrangements in B-lymphocytes

B-cells change shape in response to crosslinking of the B-cell antigen receptor (BCR). BCR signaling induces cytoskeletal rearrangements that result in cell spreading to improve antigen accumulation and B-cell activation. It has previously been shown that the gap junction protein connexin43 (Cx43) i...

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Bibliographic Details
Main Author: Falk, Letitia Louise Elizabeth
Language:English
Published: University of British Columbia 2013
Online Access:http://hdl.handle.net/2429/44327