dd-PyClone : improving clonal subpopulation inference from single cells and bulk sequencing data
Improving our understanding of intra-tumour heterogeneity in cancer has important clinical implications, including an opportunity to understand mechanisms behind relapses and drug resistance. Next generation bulk sequencing is a mature tech- nology that has been used to study subclonal tumour popula...
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| Language: | English |
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University of British Columbia
2016
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| Online Access: | http://hdl.handle.net/2429/56179 |