Development of a mass spectrometry-based method for studying hemoglobin assembly/disassembly

A mass spectrometry-based method was developed for studying hemoglobin assembly/dissociation. The dynamics of bovine hemoglobin assembly were investigated by monitoring monomers/oligomers equilibria in solution with electrospray ionization mass spectrometry and circular dichroism spectroscopy. The m...

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Bibliographic Details
Main Author: Griffith, Wendell P
Language:ENG
Published: ScholarWorks@UMass Amherst 2005
Subjects:
Online Access:https://scholarworks.umass.edu/dissertations/AAI3179878