The Role of Mitochondrial Dysfunction in Neurodegenerative Proteinopathies and Aging.
Age-related neurodegenerative proteinophaties, including polyglutamine (polyQ) diseases such as Huntington’s disease, are a group of disorders in which a single protein or a set of proteins misfold and aggregate resulting in a progressive and selective loss of anatomically or physiologically related...
Main Author: | Ocampo, Alejandro |
---|---|
Format: | Others |
Published: |
Scholarly Repository
2012
|
Subjects: | |
Online Access: | http://scholarlyrepository.miami.edu/oa_dissertations/706 |
Similar Items
-
Attenuation of polyglutamine-induced toxicity by enhancement of mitochondrial OXPHOS in yeast and fly models of aging
by: Andrea L. Ruetenik, et al.
Published: (2016-07-01) -
Mitochondrial dysfunction in the striatum of aged chronic mouse model of Parkinson's disease
by: Gaurav Patki, et al.
Published: (2009-12-01) -
Mitochondrial Dynamics: A Key Role in Neurodegeneration and a Potential Target for Neurodegenerative Disease
by: Danying Yang, et al.
Published: (2021-04-01) -
Molecular mechanisms of proteinopathies across neurodegenerative disease: a review
by: Alexander P. Marsh
Published: (2019-09-01) -
The interplay between iron accumulation, mitochondrial dysfunction and inflammation during the execution step of neurodegenerative disorders
by: Pamela J. Urrutia, et al.
Published: (2014-03-01)