Modeling of bone cell adhesion on bio-compatible surfaces, Modellering av bencellers adsorption på biokompatibla ytor
A mathematical model is presented to describe osteoblast adsorption on calcium-deficient hydroxyapatite, focusing on adsorption rate, cell survival and protein pre-incubation time. The proposed model is fitted to experimental data sets by fine-tuning the parameters for adsorption rate and cell survi...
| Main Authors: | , |
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| Format: | Others |
| Language: | English |
| Published: |
KTH, Skolan för teknikvetenskap (SCI)
2020
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| Subjects: | |
| Online Access: | http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-275652 |
| Summary: | A mathematical model is presented to describe osteoblast adsorption on calcium-deficient hydroxyapatite, focusing on adsorption rate, cell survival and protein pre-incubation time. The proposed model is fitted to experimental data sets by fine-tuning the parameters for adsorption rate and cell survival. The model was expanded to include cell division. The model produces a good fit to the data, both with and without cell division. The adsorption rate and cell survival increases with the pre-incubation time, but more data is needed to draw a valid conclusion. |
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