Mechanisms behind growth of castration-resistant prostate cancer bone metastases

Mechanisms behind growth of castration-resistant prostate cancer bone metastases

Background: The first-line treatment for patients with advanced prostate cancer (PC) is androgen deprivation therapy. This therapy is initially effective, but after some time tumors relapse, predominantly within the bone, and are then termed castration-resistant prostate cancer (CRPC). The majority...

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Bibliographic Details
Main Author: Jernberg, Emma
Format: Doctoral Thesis
Language:English
Published: Umeå universitet, Patologi 2013
Subjects:
Prostate cancer
castration-resistance
bone metastases
androgen receptor
intratumoral steroidogenesis
androgen receptor splice variants
androgen receptor amplification
Online Access:http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-83956
http://nbn-resolving.de/urn:isbn:978-91-7459-775-2

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