Design, Synthesis and Biological Evaluation of Selective Nonpeptide AT2 Receptor Agonists and Antagonists
The G protein-coupled receptors (GPCRs) are important targets in drug discovery. In several cases, the endogenous ligands that activate the GPCRs of pharmaceutical interest are peptides. Unfortunately, peptides are in general not suitable as drugs, since the peptide structure is associated with seve...
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Format: | Doctoral Thesis |
Language: | English |
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Uppsala universitet, Institutionen för läkemedelskemi
2008
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Online Access: | http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-9213 http://nbn-resolving.de/urn:isbn:978-91-554-7263-4 |