Design, Synthesis and Biological Evaluation of Selective Nonpeptide AT2 Receptor Agonists and Antagonists

The G protein-coupled receptors (GPCRs) are important targets in drug discovery. In several cases, the endogenous ligands that activate the GPCRs of pharmaceutical interest are peptides. Unfortunately, peptides are in general not suitable as drugs, since the peptide structure is associated with seve...

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Bibliographic Details
Main Author: Wallinder, Charlotta
Format: Doctoral Thesis
Language:English
Published: Uppsala universitet, Institutionen för läkemedelskemi 2008
Subjects:
Online Access:http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-9213
http://nbn-resolving.de/urn:isbn:978-91-554-7263-4

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