Structural Studies of Glutamine Synthetases – Towards the Development of Novel Antitubercular Agents
Glutamine synthetase (GS) plays an important role in nitrogen metabolism, where it catalyzes the ATP-dependent condensation of glutamate and ammonia to yield glutamine. Recent studies showed the importance of M. tuberculosis GS (MtGS) for growth and survival of the bacterium, and demonstrated its po...
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| Format: | Doctoral Thesis |
| Language: | English |
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Uppsala universitet, Strukturell molekylärbiologi
2008
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| Online Access: | http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-9286 http://nbn-resolving.de/urn:isbn:978-91-554-7283-2 |