Role of c-Jun N-terminal kinase (JNK) in mediating mammary cancer cell migration and metastasis

The c-Jun N-terminal kinases (JNKs) are MAPK family members and are activated by stress, growth factors and cytokines. They are encoded by three separate genes (jnk 1, 2, and 3), spliced alternately creating 10 isoforms. JNK signaling promotes both cell death and cell survival in a stimuli and tiss...

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Bibliographic Details
Main Author: Mitra, Shreya
Format: Others
Language:English
Published: 2012
Subjects:
Online Access:http://hdl.handle.net/2152/18422