Engineering a novel human methionine degrading enzyme as a broadly effective cancer therapeutic
Many cancers have long been known to display an absolute requirement for the amino acid methionine (L-Met). Studies have shown that in the absence of L-Met, sensitive neoplasms experience cell cycle arrest and perish. Without the metabolic deviations that characterize L-Met auxotrophs, normal cells...
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| Format: | Others |
| Language: | en |
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2015
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| Online Access: | http://hdl.handle.net/2152/31302 |