Studies on the mechanism of action of thyroid hormones
Inosine monophosphate (IMP) is a precursor of the two purine nucleotides, adenosine monophosphate (AMP) and guanosine monophosphate (GMP)e through DEAE-Scphacex, and the reaction IMP~ XMP is catalyzed by: IMP dehydrogenase which was purified in a manner similar to adenylosuccinate synthetase. Adenyl...
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| Format: | Others |
| Language: | en |
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Virginia Tech
2014
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| Online Access: | http://hdl.handle.net/10919/25994 http://scholar.lib.vt.edu/theses/available/etd-01132010-020024/ |
| Summary: | Inosine monophosphate (IMP) is a precursor of the two purine nucleotides, adenosine monophosphate (AMP) and guanosine monophosphate (GMP)e through DEAE-Scphacex, and the reaction IMP~ XMP is catalyzed by: IMP dehydrogenase which was purified in a manner similar to adenylosuccinate synthetase. Adenylosuccinate synthetase of rat liver is stimulated maximally with 10-9 M L-T 3 or 10-5 M L-T4 , but not by D in vivo effects. Further correlation to in vivo studies was obtained from brain and testes tissues. === Ph. D. |
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