Studies on the mechanism of action of thyroid hormones

• Main Author: Al-Mudhaffar, Semi Abdul-Mohdi
• Other Authors: Biochemistry
• Format: Others
• Language: en
• Published: Virginia Tech 2014
• Subjects: enzymes; thyroid hormones; LD5655.V856 1967.M8
• Online Access: http://hdl.handle.net/10919/25994; http://scholar.lib.vt.edu/theses/available/etd-01132010-020024/

Inosine monophosphate (IMP) is a precursor of the two purine nucleotides, adenosine monophosphate (AMP) and guanosine monophosphate (GMP)e through DEAE-Scphacex, and the reaction IMP~ XMP is catalyzed by: IMP dehydrogenase which was purified in a manner similar to adenylosuccinate synthetase. Adenylosuccinate synthetase of rat liver is stimulated maximally with 10-9 M L-T 3 or 10-5 M L-T4 , but not by D in vivo effects. Further correlation to in vivo studies was obtained from brain and testes tissues. === Ph. D.