Neural Tube Defect-causing Teratogens Affect Tissue Mechanical Properties and Cytoskeletal Morphology in Axolotl Embryos
The teratogenic drugs cytochalasin B and valproic acid have been shown to alter F-actin polymerization, an effect that is crucial in forming microfilaments. Microfilaments form important cytoskeletal structures that maintain the structural integrity of the cell, cause cell motility and cell migratio...
| Main Author: | |
|---|---|
| Language: | en |
| Published: |
2007
|
| Subjects: | |
| Online Access: | http://hdl.handle.net/10012/3426 |