Liver injury in hypervitaminosis A: Evidence for activation of Kupffer cell function.

The most important and novel finding of this work was enhanced liver Kupffer cell phagocytic and metabolic function by hypervitaminosis A. An animal model of hypervitaminosis A was developed in male Sprague-Dawley rats gavaged with 250,000 I.U. retinol/Kg body weight/day for 3 weeks. Presence of hyp...

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Bibliographic Details
Main Author: Sim, Wai-Lum Winnie.
Other Authors: Earnest, David L.
Language:en
Published: The University of Arizona. 1988
Subjects:
Online Access:http://hdl.handle.net/10150/184410

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