System Integration - A Major Step toward Lab on a Chip

System Integration - A Major Step toward Lab on a Chip

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Microfluidics holds great promise to revolutionize various areas of biological engineering, such as single cell analysis, environmental monitoring, regenerative medicine, and point-of-care diagnostics. Despite the fact that intensive efforts have been devoted into the field in the past decades, micr...

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Main Authors: Sin, Mandy, Gao, Jian, Liao, Joseph, Wong, Pak
Other Authors: Department of Aerospace and Mechanical Engineering, University of Arizona, Tucson, AZ 85721, USA
Language:en
Published: BioMed Central 2011
Online Access:Sin et al. Journal of Biological Engineering 2011, 5:6 http://www.jbioleng.org/content/5/1/6
http://hdl.handle.net/10150/610170
http://arizona.openrepository.com/arizona/handle/10150/610170
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spelling ndltd-arizona.edu-oai-arizona.openrepository.com-10150-6101702016-05-22T03:01:44Z System Integration - A Major Step toward Lab on a Chip Sin, Mandy Gao, Jian Liao, Joseph Wong, Pak Department of Aerospace and Mechanical Engineering, University of Arizona, Tucson, AZ 85721, USA Department of Chemical Engineering, Shandong Polytechnic University, Jinan, 250353, China Department of Urology, Stanford University, 300 Pasteur Drive, S-287, Stanford, CA 94305, USA Biomedical Engineering and Bio5 Institute, University of Arizona, Tucson, AZ 85721, USA Microfluidics holds great promise to revolutionize various areas of biological engineering, such as single cell analysis, environmental monitoring, regenerative medicine, and point-of-care diagnostics. Despite the fact that intensive efforts have been devoted into the field in the past decades, microfluidics has not yet been adopted widely. It is increasingly realized that an effective system integration strategy that is low cost and broadly applicable to various biological engineering situations is required to fully realize the potential of microfluidics. In this article, we review several promising system integration approaches for microfluidics and discuss their advantages, limitations, and applications. Future advancements of these microfluidic strategies will lead toward translational lab-on-a-chip systems for a wide spectrum of biological engineering applications. 2011 Article Sin et al. Journal of Biological Engineering 2011, 5:6 http://www.jbioleng.org/content/5/1/6 10.1186/1754-1611-5-6 http://hdl.handle.net/10150/610170 http://arizona.openrepository.com/arizona/handle/10150/610170 1754-1611 Journal of Biological Engineering en http://www.jbioleng.org/content/5/1/6 © 2011 Sin et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0) BioMed Central
collection NDLTD
language en
sources NDLTD
description Microfluidics holds great promise to revolutionize various areas of biological engineering, such as single cell analysis, environmental monitoring, regenerative medicine, and point-of-care diagnostics. Despite the fact that intensive efforts have been devoted into the field in the past decades, microfluidics has not yet been adopted widely. It is increasingly realized that an effective system integration strategy that is low cost and broadly applicable to various biological engineering situations is required to fully realize the potential of microfluidics. In this article, we review several promising system integration approaches for microfluidics and discuss their advantages, limitations, and applications. Future advancements of these microfluidic strategies will lead toward translational lab-on-a-chip systems for a wide spectrum of biological engineering applications.
author2 Department of Aerospace and Mechanical Engineering, University of Arizona, Tucson, AZ 85721, USA
author_facet Department of Aerospace and Mechanical Engineering, University of Arizona, Tucson, AZ 85721, USA
Sin, Mandy
Gao, Jian
Liao, Joseph
Wong, Pak
author Sin, Mandy
Gao, Jian
Liao, Joseph
Wong, Pak
spellingShingle Sin, Mandy
Gao, Jian
Liao, Joseph
Wong, Pak
System Integration - A Major Step toward Lab on a Chip
author_sort Sin, Mandy
title System Integration - A Major Step toward Lab on a Chip
title_short System Integration - A Major Step toward Lab on a Chip
title_full System Integration - A Major Step toward Lab on a Chip
title_fullStr System Integration - A Major Step toward Lab on a Chip
title_full_unstemmed System Integration - A Major Step toward Lab on a Chip
title_sort system integration - a major step toward lab on a chip
publisher BioMed Central
publishDate 2011
url Sin et al. Journal of Biological Engineering 2011, 5:6 http://www.jbioleng.org/content/5/1/6
http://hdl.handle.net/10150/610170
http://arizona.openrepository.com/arizona/handle/10150/610170
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AT gaojian systemintegrationamajorsteptowardlabonachip
AT liaojoseph systemintegrationamajorsteptowardlabonachip
AT wongpak systemintegrationamajorsteptowardlabonachip
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