The nitroxyl donor, Angeli's salt, reduces chronic constriction injury-induced neuropathic pain.

The nitroxyl donor, Angeli's salt, reduces chronic constriction injury-induced neuropathic pain.

Chronic pain is a major health problem worldwide. We have recently demonstrated the analgesic effect of the nitroxyl donor, Angeli's salt (AS) in models of inflammatory pain. In the present study, the acute and chronic analgesic effects of AS was investigated in chronic constriction injury of t...

Full description

Bibliographic Details
Main Authors:	Longhi-Balbinot, Daniela T, Rossaneis, Ana C, Pinho-Ribeiro, Felipe A, Bertozzi, Mariana M, Cunha, Fernando Q, Alves-Filho, José C, Cunha, Thiago M, Peron, Jean P S, Miranda, Katrina M, Casagrande, Rubia, Verri, Waldiceu A
Other Authors:	Univ Arizona, Dept Chem & Biochem
Language:	en
Published:	ELSEVIER IRELAND LTD 2016
Subjects:	Nitroxyl donor Neuropathic pain Astrocytes Microglia Cytokines
Online Access:	http://hdl.handle.net/10150/621523 http://arizona.openrepository.com/arizona/handle/10150/621523

Similar Items

SYNTHESIS OF NEW PHOTOACTIVATABLE NITROXYL (HNO) DONORS BASED ON THE 6,2-HNM PHOTOTRIGGER
by: Brandle, Greggory C.
Published: (2018)

Effects of pH on the Autoxidation of Nitroxyl
by: Buttitta, Lisa Ann
Published: (2012)

Diabetes Attenuates the Contribution of Endogenous Nitric Oxide but Not Nitroxyl to Endothelium Dependent Relaxation of Rat Carotid Arteries
by: Jasmin Chendi Li, et al.
Published: (2021-01-01)

Synthetic Explorations in the Pursuit of a Rapid, Photoactivatable, Nitroxyl Donor
by: Campbell, Mark Wesley
Published: (2017)

Fumagillin Attenuates Spinal Angiogenesis, Neuroinflammation, and Pain in Neuropathic Rats after Chronic Constriction Injury
by: Zhi-Hong Wen, et al.
Published: (2021-09-01)

Induction of caveolin-3/eNOS complex by nitroxyl (HNO) ameliorates diabetic cardiomyopathy
by: Hai-Jian Sun, et al.
Published: (2020-05-01)

Nitric Oxide- and Nitroxyl-Releasing Diazeniumdiolates in Pharmaceutical and Biomedical Research Applications
by: Salmon, Debra J.
Published: (2011)

Electrochemical Oxidation of Amines Using a Nitroxyl Radical Catalyst and the Electroanalysis of Lidocaine
by: Katsuhiko Sato, et al.
Published: (2018-12-01)

The Role of Phospholamban Cysteines in the Activation of the Cardiac Sarcoplasmic Reticulum Ca2+ Pump by Nitroxyl (HNO)
by: Thorpe, Chevon N.
Published: (2014)

In Vitro and in Vivo Imaging of Nitroxyl with Copper Fluorescent Probe in Living Cells and Zebrafish
by: Sathyadevi Palanisamy, et al.
Published: (2018-10-01)

Koumine Decreases Astrocyte-Mediated Neuroinflammation and Enhances Autophagy, Contributing to Neuropathic Pain From Chronic Constriction Injury in Rats
by: Gui-lin Jin, et al.
Published: (2018-08-01)

Elucidation of the quinone methide tautomer of riboflavin and generation of a flavin nitroxyl radical
by: Frost, John Wesley
Published: (2005)

Nitroxyl: A Novel Strategy to Circumvent Diabetes Associated Impairments in Nitric Oxide Signaling
by: Anida Velagic, et al.
Published: (2020-05-01)

Delayed-onset Polymer Cross-linking using Functional Nitroxyls
by: Hyslop, David
Published: (2012)

CXL-1020, a Novel Nitroxyl (HNO) Prodrug, Is More Effective than Milrinone in Models of Diastolic Dysfunction—A Cardiovascular Therapeutic: An Efficacy and Safety Study in the Rat
by: Steve R. Roof, et al.
Published: (2017-11-01)

Mechanisms Associated to Nitroxyl (HNO)-Induced Relaxation in the Intestinal Smooth Muscle
by: Mirko Gastreich-Seelig, et al.
Published: (2020-06-01)

A model of neuropathic pain in brachial plexus avulsion injury and associated spinal glial cell activation
by: Hou AL, et al.
Published: (2018-12-01)

The Role of Satellite Glial Cells, Astrocytes, and Microglia in Oxaliplatin-Induced Neuropathic Pain
by: Ji Hwan Lee, et al.
Published: (2020-09-01)

Effect of ethosucximide on the reduction of neuropathic pain due to chronic constriction of the sciatic nerve in rats
by: Gholam Ali Hamidi, et al.
Published: (2013-05-01)

Effect of biotin supplementation on neuropathic pain induced by chronic constriction of the sciatic nerve in the rat
by: Ali-Reza Abed, et al.
Published: (2021-01-01)

The Effect of Ethanolic Extract of Lippia Citriodora on Rats with Chronic Constriction Injury of Neuropathic pain
by: Bahareh Amin, et al.
Published: (2017-11-01)

Etude du greffage radicalaire de l'anhydride maléique sur le polyéthylène en milieu fondu et en présence de radicaux nitroxyle et/ou d'alcoxyamines
by: Belekian, Denis
Published: (2012)

Repeated electroacupuncture treatment attenuated hyperalgesia through suppression of spinal glial activation in chronic neuropathic pain rats
by: Jun-ying Wang, et al.
Published: (2018-02-01)

Effects of aminoguanidin on the neuropathic behavioral responses of chronic constriction injury model in rat
by: Mohammad Hadi Yarigarravesh, et al.
Published: (2009-05-01)

Inflammation-associated regulation of RGS in astrocytes and putative implication in neuropathic pain
by: Pierre J. Doyen, et al.
Published: (2017-10-01)

Fe3O4@Polydopamine-Labeled MSCs Targeting the Spinal Cord to Treat Neuropathic Pain Under the Guidance of a Magnetic Field
by: Liu M, et al.
Published: (2021-05-01)

Functionalizations of Diamantane Dimers
by: Pavel A. Gunchenko, et al.
Published: (2020-05-01)

Ninjin'yoeito Alleviates Neuropathic Pain Induced by Chronic Constriction Injury in Rats
by: Risa Takemoto, et al.
Published: (2021-02-01)

TLR4-mediated autophagic impairment contributes to neuropathic pain in chronic constriction injury mice
by: Yibo Piao, et al.
Published: (2018-02-01)

Astrocyte activation in the anterior cingulate cortex and altered glutamatergic gene expression during paclitaxel-induced neuropathic pain in mice
by: Willias Masocha
Published: (2015-10-01)

Intrathecal interleukin-1β decreases sigma-1 receptor expression in spinal astrocytes in a murine model of neuropathic pain
by: Sheu-Ran Choi, et al.
Published: (2021-12-01)

Pregnancy suppresses neuropathic pain induced by chronic constriction injury in rats through the inhibition of TNF-α
by: Onodera Y, et al.
Published: (2017-03-01)

Aloin attenuates chronic constriction injury-induced neuropathic pain in rats by inhibiting inflammatory cytokines and oxidative stress
by: Aarti S Kale, et al.
Published: (2021-01-01)

Modulation of Cardiac Contraction by Reactive Nitrogen Species
by: Kohr, Mark Jeffrey, Jr.
Published: (2009)

Attenuation of neuropathic pain by sodium butyrate in an experimental model of chronic constriction injury in rats
by: Ankesh Kukkar, et al.
Published: (2014-12-01)

Lipid rafts in glial cells: role in neuroinflammation and pain processing
by: Yury I. Miller, et al.
Published: (2020-05-01)

Central neuropathic pain
by: João Batista Santos Garcia, et al.

Intraneural Application of microRNA-1 Mimetic Nucleotides Does Not Resolve Neuropathic Pain After Chronic Constriction Injury in Rats
by: Kuebart A, et al.
Published: (2020-11-01)

Botulinum Toxin for the Treatment of Neuropathic Pain
by: JungHyun Park, et al.
Published: (2017-08-01)

Forced exercise attenuates neuropathic pain in chronic constriction injury of male rat: an investigation of oxidative stress and inflammation
by: Safakhah HA, et al.
Published: (2017-06-01)