Pim1 kinase regulates c-Kit gene translation

Pim1 kinase regulates c-Kit gene translation

Background: Receptor tyrosine kinase, c-Kit (CD117) plays a pivotal role in the maintenance and expansion of hematopoietic stem/progenitor cells (HSPCs). Additionally, over-expression and/or mutational activation of c-Kit have been implicated in numerous malignant diseases including acute myeloid le...

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Bibliographic Details
Main Authors:	An, Ningfei, Cen, Bo, Cai, Houjian, Song, Jin H., Kraft, Andrew, Kang, Yubin
Other Authors:	Univ Arizona, Ctr Canc
Language:	en
Published:	BIOMED CENTRAL LTD 2016
Subjects:	Receptor tyrosine kinase c-Kit PIM kinase Serine/threonine kinase Translation Regulation Hematopoiesis Hematopoietic stem cells Hematopoietic progenitor cells
Online Access:	http://hdl.handle.net/10150/622957 http://arizona.openrepository.com/arizona/handle/10150/622957

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