Studies of the PTEN tumour suppressor in endometrial cancer

Somatic mutations in the PTEN gene (Phosphatase and Tensin Homologue Deleted on Chromosome Ten) have been found in many types of cancer, but most frequently in cancer of the endometrium. The PTEN gene encodes a D3 lipid phosphatase of the second messenger phosphatidylinositol 3,4,5-trisphosphate (PI...

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Bibliographic Details
Main Author: Crosland, Rachel
Other Authors: Blair, Maria ; Wells, Mike
Published: Sheffield Hallam University 2004
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.399430