Molecular mechanisms in down-regulation of IL-10 gene expression by IFN-gamma

Interleukin-10 (IL-10) is a suppressive cytokine that down-regulates immune response and inflammation. It was shown previously that IL-10 expression is up-regulated after stimulation with LPS and that IFNgamma is able to down-regulate LPS-induced IL-10 expression.;In the present study, the cis- and...

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Bibliographic Details
Main Author: Schaefer, Annette
Published: University of Leicester 2005
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.431839