Preparation and exploitation of tailored polymer resins for use in dynamic combinatial library synthesis
The thermodynamically controlled synthesis, amplification and isolation of macrocydic receptors from dynamic combinatorial libraries (DCLs) has been achieved in a single step using polymer-supported templates. By combining synthesis and affinity chromatography into one single step tedious separation...
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ndltd-bl.uk-oai-ethos.bl.uk-4885142015-03-20T05:31:02ZPreparation and exploitation of tailored polymer resins for use in dynamic combinatial library synthesisBesenius, Pol2008The thermodynamically controlled synthesis, amplification and isolation of macrocydic receptors from dynamic combinatorial libraries (DCLs) has been achieved in a single step using polymer-supported templates. By combining synthesis and affinity chromatography into one single step tedious separations via chromatographic techniques can be avoided, which opens new preparative possibilities especially in more complex libraries comprising an increased number of building blocks.547.5University of Strathclydehttp://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.488514Electronic Thesis or Dissertation |
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547.5 Besenius, Pol Preparation and exploitation of tailored polymer resins for use in dynamic combinatial library synthesis |
description |
The thermodynamically controlled synthesis, amplification and isolation of macrocydic receptors from dynamic combinatorial libraries (DCLs) has been achieved in a single step using polymer-supported templates. By combining synthesis and affinity chromatography into one single step tedious separations via chromatographic techniques can be avoided, which opens new preparative possibilities especially in more complex libraries comprising an increased number of building blocks. |
author |
Besenius, Pol |
author_facet |
Besenius, Pol |
author_sort |
Besenius, Pol |
title |
Preparation and exploitation of tailored polymer resins for use in dynamic combinatial library synthesis |
title_short |
Preparation and exploitation of tailored polymer resins for use in dynamic combinatial library synthesis |
title_full |
Preparation and exploitation of tailored polymer resins for use in dynamic combinatial library synthesis |
title_fullStr |
Preparation and exploitation of tailored polymer resins for use in dynamic combinatial library synthesis |
title_full_unstemmed |
Preparation and exploitation of tailored polymer resins for use in dynamic combinatial library synthesis |
title_sort |
preparation and exploitation of tailored polymer resins for use in dynamic combinatial library synthesis |
publisher |
University of Strathclyde |
publishDate |
2008 |
url |
http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.488514 |
work_keys_str_mv |
AT beseniuspol preparationandexploitationoftailoredpolymerresinsforuseindynamiccombinatiallibrarysynthesis |
_version_ |
1716791802248298496 |