Pathogenesis of core binding factor in acute and chronic myeloproliferative disorders

Pathogenesis of leukaemia is a multistep process that involves multiple genetic alterations of normal cells to transform into a malignant phenotype. Mutations in the receptor tyrosine kinase (RTK/RAS) signalling pathway frequently provide a proliferative signal particularly the core binding factors...

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Bibliographic Details
Main Author: Johan, Muhammad Farid
Published: University of Sheffield 2007
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.490188